In the fight against peptic ulcer and gastritis, many patients are looking for an effective and affordable medicine. Omeprazole is just such a remedy. Due to its ability to inhibit acid secretion, hydrochloric acid quickly suppresses discomfort and pain. In addition to the original medicine, there are many generics and analogues of Omeprazole, not inferior in their therapeutic properties. They are produced by many countries and have a beneficial effect on the secretion of gastric juice.

Composition (active substance) of omeprazole

The active component of the drug is omeprazole. It refers to proton pump inhibitors. Inhibition of secretion is based on the ability to reduce the active work of parietal cells. And due to a decrease in activity, the production of acid by the stomach is blocked. The therapeutic effect of the drug occurs within 1-2 hours after administration.

IMPORTANT! Omeprazole is a modern, modified form of composition. It is the so-called prodrug - a tool that, under the influence of the biological activity of the human body, turns into a full-fledged medicine.

Auxiliary components: medical gelatin, titanium dioxide, glycerin, purified water, “Charming Red AS” dye, sodium lauryl sulfate.

Indications for use

Specialists prescribe the use of the drug for treatment in cases where there is an increased secretion of hydrochloric acid in the stomach cavity. Hypersecretion causes not only changes on the walls of this organ, but also often affects the duodenum 12, esophagus.

When omeprazole is indicated:

  • peptic ulcer (stomach and duodenal ulcer);
  • conditions caused by hypersecretion (stress ulcers, pancreas, ulcerogenic adenoma, systemic mastocytosis, polyendocrine adenomatosis);
  • gastroesophageal reflux disease (GERD or reflux esophagitis);
  • gastropathy caused by taking NSAIDs;
  • prevention of acid-aspiration pneumonitis (throwing the contents of the stomach into the lower respiratory tract during general anesthesia);
  • erosive esophagitis;
  • gastritis (with an increase in acidity);
  • pancreatitis

As part of combination therapy, it is used to remove Helicobacter pylori from the surface of mucous membranes in people with peptic ulcer disease.

IMPORTANT! With dyspeptic disorders (heartburn), the drug is used to prevent acidity and to stop an attack of heartburn.

Russian analogues of the drug

In the Russian pharmaceutical market there are many drugs that will successfully replace the original drug. Among them are both structural analogues from different companies, and drugs with a similar therapeutic effect.

Qualitative structural substitutes for Omeprazole in the domestic market:

  • Omeprazole Acry. Available in capsules of 20 mg. Manufacturer - HFK Akrikhin OJSC. Price from 57 rubles;
  • Omeprazole Stada. Available in capsules of 20 mg. Manufacturer - CJSC Skopinsky Pharmaceutical Plant. Price from 140 rubles;
  • Gastrozole. A similar form of release. Manufacturer - Pharmstandard OJSC;
  • Omeprazole Available in the form of a lyophilisate for the preparation of infusion solutions. In one bottle 40 mg of the active ingredient. Manufacturer - GC "MIR-PHARM".

Russian analogues in therapeutic effect:

  • Rabeprazole The active substance is rabeprazole sodium. It is an inhibitor of the proton pump, but has a more pronounced effect on hypersecretion. Promotes rapid healing of tissues. Available in capsules of 10 mg. Producer - CJSC FP OBOLENSKY. Price from 125 rubles;
  • Ranitidine-Akos. The active substance is ranitidine hydrochloride. Refers to H2 antihistamines. Helps inhibit acid secretion caused by gastrin, histamine, and ACC. Available in tablets of 150 and 300 mg. Manufacturer - Synthesis CJSC. The price is from 18 rubles.

Imported Drug Substitutes

A lot of medicines are coming into the Russian pharmaceutical market from abroad that can replace the original Omeprazole. They have a high price, but the quality and therapeutic effect justify it.

Good modern analogues of imported origin will successfully replace Omeprazole capsules:

  • Nolpaza. The active ingredient is pantoprazole. Refers to proton pump inhibitors, can reduce the secretion of hydrochloric acid. Available in the form of tablets and lyophilisate for the preparation of a solution. The producer - "Krka", Slovenia. Price from 170 rubles;
  • Esolong The active substance is esoprozole. Refers to proton pump inhibitors. 20 and 40 mg tablets. Manufacturer - Optimus Generics Limited, India;
  • Soars. The active substance is rabeprazole. Refers to proton pump inhibitors. Tablets of 10 and 20 mg. Manufacturer - “ASAI Co. Limited, Japan, commissioned by Johnson and Johnson, RF. The price is from 850 rubles.

Modern generics without side effects

Unfortunately, there is not a single analogue of Omeprazole that would not cause side effects. But thanks to modern technology, manufacturers have learned to minimize unpleasant symptoms in patients. Now, side effects are less common and are less severe.

Modern generic Omeprazole:

  • Omez D. Reduces secretory activity, increases the peristalsis of the intestines and increases the tone of the esophagus sphincters. Producer: "Doctor Reddis", India. Contraindications: hypersensitivity to the components, intestinal obstruction, gastrointestinal bleeding, severe renal and hepatic impairment. Side effects: abdominal pain, dyspeptic symptoms, general weakness. The cost is about 265 rubles;
  • Losek MAPS. Reduces the secretory activity of the stomach, the effect is dose-dependent. Producer: "LEK", Slovenia. Contraindications: hypersensitivity to the components, glucose-galactose malabsorption, fructose intolerance, sucrose deficiency. Side effects: nausea, vomiting, headaches and abdominal pains, weakness, diarrhea or constipation. The cost is about 1160 rubles;
  • Ultop. Inhibition of secretion without anticholinergic action. Producer: "KRKA", Slovenia. Contraindications: children under 12 years of age, hypersensitivity to components, a history of malignant neoplasms. Side effects: nausea, vomiting, abdominal pain, change in stool, dizziness. The cost is about 623 rubles;
  • Orthanol. Reduces the secretory activity of the stomach and eliminates the symptoms of gastroesophageal reflux. Producer: "Sandoz", Austria. Contraindications: hypersensitivity to components, lactase deficiency, malabsorption syndrome and other forms of hereditary intolerance, children's age. Side effects: nausea, vomiting, dyspeptic disorders, headache, increased sweating. The cost is about 343 rubles.

 

Modern analogues and generics can successfully replace Omeprazole in one case or another. It is worth noting that the decision to replace the medicine is made only by the attending physician. It is not enough to study the instructions for use, it is important to understand the mechanism of action of the analogue. Self-correction of therapy can lead to the development of adverse reactions and worsen health problems.

Related:More from the author: